In-house Office solution developers should have access to the 64-bit Office 2016 for testing and updating these solutions. Using the 64-bit version of Office lets you deliver a 64-bit version of those solutions as well as a 32-bit version.
You’re developing in-house Office solutions like add-ins or document-level customization. You’re working with files over 2 GB in Project, especially if the project has many sub-projects. The 64-bit version of Office may be better suited to handle these complex slide decks. You’re working with extremely large pictures, videos, or animations in PowerPoint. See, Excel specifications and limits, Data Model specification and limits, and Memory usage in the 32-bit edition of Excel. The 64-bit version of Office may perform better in these cases. 
You’re working with large data sets, like enterprise-scale Excel workbooks with complex calculations, many pivot tables, data connections to external databases, Power Pivot, 3D Map, Power View, or Get & Transform. Some examples of where 64-bit Office is particularly useful: 64-bit operating system can handle large amounts of memory, so a 64-bit system can be more responsive when running several programs at the same time and switching between them frequently. The benefits of using a 64-bit Windows and Office are most apparent when you have a large amount of random access memory (RAM) installed on your computer, typically 4 GB of RAM or more. Oddly the Office 365 message centre message was published, then disappeared for a while, but now is back. from now mid-Jan 2019 forward both Office ProPlus (the continuously updating subscription version from Office 365) and Office 2019 (the version you buy “in a box” but also actually click to run). 
The default Office 365 click to run install was indeed 32-bit regardless of your OS version, until now. It was initially recommended to run 32-bit Office as all the Office plugins were typically written for 32-bit, you were only recommended to run 64-bit if you needed to address a lot of RAM, for example running large spreadsheets. You might think the 32-bit version was for 32-bit Windows and the 64-bit for 64-bit windows, but 64-bit windows can run actually run 32-bit Office fine, Since Office 2010, Microsoft has offered a 32-bit install and a 64-bit Office install.
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